Caenorhabditis elegans screening assay in microbiology

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Scope of the method

The Method relates to

Human health

The Method is situated in

Basic Research
Education and training
Translational - Applied Research

Type of method

In vivo

Used species

Caenorhabditis elegans

Description

Method keywords

microbiology
infection
antibiotics
virulence
biofilm

Scientific area keywords

microbiology
antibiotics
infection
screening
virulence
biofilm

Method description

The C. elegans assay can be used to study the virulence of various microorganisms, and can be used to evaluate the antimicrobial effect of drugs or drug candidates. The two main outcome parameters are (i) survival of C. elegans and (ii) microbial load.

Lab equipment

Basic microbiology lab equipment.

Method status