In the skillslab, dummy models and simulators are used for teaching various clinical skills. The veterinarians in training need to learn how to perform different bandaging techniques in small and large animals. Although training on living animals is important, a part of the training proces can be
Last updated on: 10-02-2023 - 16:12
Contact: Annelies Decloedt
Organisation: Ghent University (UGent)
Status: History of use, Internally validated
This method is used to let cells interact for a better simulation of processes occurring in the body. The rational of the method is that monoculture experiments do not capture the complexity of in vivo interactions between different organs. In the most simple setup (published work Nutrients), Caco-2
Last updated on: 09-02-2023 - 16:37
Contact: Amar van Laar
Organisation: Ghent University (UGent)
Status: Published in peer reviewed journal
In the skillslab, dummy models and simulators are used for teaching various clinical skills such as sutures, injections, … The veterinarians in training start with practising basic skills such as handling animals, and progress over the years to perform more complex procedures on simulators such as
Last updated on: 08-02-2023 - 14:18
Contact: Annelies Decloedt
Organisation: Ghent University (UGent)
Status: History of use, Internally validated
We devised a simple and reliable method for reprogramming peripheral blood mononuclear cells into hiPSC and then to differentiate them into air-liquid interface bronchial epithelium (iALI) within 45 days. Of note, this method does not involve any cell sorting step. We reprogrammed blood cells from
Last updated on: 07-02-2023 - 14:46
Contact: Engi Ahmed
Organisation: VIB - UGent, IRMB INSERM 1183
Status: History of use, Internally validated, Published in peer reviewed journal
The purpose of the present development is to use avian MoDCs to implement a cellular platform to increase understanding of the immune responses induced by various antigens of interest (e.g. vaccine candidates) and evaluate their immunogenic potential. Considering the difficulty to work on dendritic
Last updated on: 03-02-2023 - 08:51
Ex-vivo tissue explants (precision cut tissue slices) prepared with the Krumdieck Tissue Slicer are living, three-dimensional tissue slices closely resemble the organ from which it is prepared, with all the cell types present in their original tissue-matrix configuration where physiological and
Last updated on: 31-01-2023 - 15:52
Human Intestinal Organoids (HIOs) are in vitro 3D cell cultures arranged in a crypt-villus structure that incorporate many physiological features of the intestinal epithelium, including the presence of different cell populations (enterocytes, goblet cells, enteroendocrine and Paneth cells). HIOs can
Last updated on: 27-01-2023 - 13:29
Contact: Joana Rocha-Pereira
Organisation: Katholieke Universiteit Leuven (KUL)
Status: Published in peer reviewed journal
Intestinal organoids are cultured from intestinal biopsies obtained during routine endoscopy. The stem cell containing crypts are isolated and cultured in a 3D ECM (Matrigel) in the presence of the desired growth factors. The present stem cells will expand and give rise to all epithelial cells of
Last updated on: 11-01-2023 - 16:43
Contact: Bram Verstockt
Organisation: Katholieke Universiteit Leuven (KUL)
Status: Published in peer reviewed journal
Myeloid progenitor cells derived from the bone marrow of mice are stimulated using a cytokine mixture to become myeloid derived suppressor cell (MDSC) like cells. These are co-cultured with activated CD8+ T-cells derived from a mouse spleen. The MDSC like cells will suppress the proliferation of the
Last updated on: 10-01-2023 - 16:48
Contact: Yani Berckmans
Organisation: Katholieke Universiteit Leuven (KUL), Oncology - KU Leuven
Status: History of use, Published in peer reviewed journal
This study aimed to create a versatile and reproducible in vitro model of a human motor unit with functional neuromuscular junctions (NMJs). Therefore, human induced pluripotent stem cell (hiPSC)-derived motor neurons and human primary mesoangioblast (MAB)-derived myotubes were co-cultured in
Last updated on: 09-01-2023 - 15:13
Contact: Katarina Stoklund Dittlau
Organisation: Vlaams Instituut voor Biotechnologie (VIB), Katholieke Universiteit Leuven (KUL), Neurosciences - KU Leuven
Status: Published in peer reviewed journal
