iPSC derived neuronal cultures

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Scope of the method

The Method relates to
  • Human health
The Method is situated in
  • Basic Research
  • Translational - Applied Research
Type of method
  • In vitro - Ex vivo
This method makes use of
  • Animal derived cells / tissues / organs
Species from which cells/tissues/organs are derived
human - control and patient
Type of cells/tissues/organs
cortical glutamatergic and inhibitory neurons - astrocytes

Description

Method keywords
  • iPSC-derived neurons
Scientific area keywords
  • neurodevelopmental disorders
  • neurobiology
  • Disease modelling
Method description

We generate iPSC derived neurons and astrocytes using NgN2, ASCL1 and SOX9 overexpression respectively.

Method status
  • Published in peer reviewed journal

Contact person

Sarah Weckhuysen

Organisations

Vlaams Instituut voor Biotechnologie (VIB)
Center for Molecular Neurology
Epilepsy Genetics
Belgium
Flemish Region

University of Antwerp (UAntwerpen)
Translational Neuroscience
Epilepsy Genetics
Belgium
Flemish Region