Dermatophyte infection of Reconstructed Human Epidermis
Commonly used acronym: RHE
Scope of the method
The Method relates to
- Human health
The Method is situated in
- Basic Research
Type of method
- In vitro - Ex vivo
This method makes use of
- Human derived cells / tissues / organs
Specify the type of cells/tissues/organs
Human epidermal keratinocytes and Trichophyton rubrum spores
Description
Method keywords
- Dermatophytes
- fungal infection
- tinea
Scientific area keywords
- dermatology
- mycology
Method description
The method is about infection of human epidermis in culture by anthropophilic dermatophytes of Trichophyton rubrum species.
Lab equipment
Culture hood, incubators for cell culture, refrigerated centrifuge.
Method status
- Published in peer reviewed journal
Pros, cons & Future potential
Advantages
Allows ethically acceptable infection of human tissues.
Challenges
Currently, there is no immune cell or adaptative immunity in the model.
References, associated documents and other information
Associated documents
Faway 2016 Med Mycol55-485.pdf
Faway2019-JID139-2080 + suppl.pdf
FawayStaerck2021 jof-07-01029-v2.pdf
Contact person
Yves PoumayOrganisations
Université de Namur (UNamur)NARILIS
Belgium
Walloon
