Monotonic dose-response testing for Nanomaterial toxicity
Commonly used acronym: NMTox
Scope of the method
- Animal health
- Human health
- Basic Research
- Translational - Applied Research
- In silico
- Animal derived cells / tissues / organs
- data exploration
- dose response
- monotonic trend
NMTox is an R-software package and a Shiny app that can be used to explore and subset large datasets and can identify and test for monotonic dose responses. The package was developed within the NanoInformaTIX project where a platform is developed that aims to predict nanomaterial toxicity.
- Internally validated
Pros, cons & Future potential
Versatile tool to be used for several applications.
Learning curve if the R-package is used.
References, associated documents and other information
Contact personGeert Verheyen
OrganisationsThomas More University of Applied Sciences
University of Hasselt (UHasselt)
Centrum voor Statistiek