Through leveraging our combined computational and biological knowledge, we have proven expertise supporting clients in:
(1) Tailored analysis of single-cell data that incorporates relevant biological information, including application of AI and machine learning,
(2) Studying the stochastic
Last updated on: 11-03-2024 - 13:31
Contact: Cannot be disclosed
Organisation: BioLizard
Status: History of use, Internally validated, Validated by an external party (e.g. OECD, EURL ECVAM,…)
We have implemented the use of 3D patient-derived tumor organoids, to study metabolic (dys)functions associated with tumor development and progression, including response to anticancer therapies. These sophisticated models allow to better integrate the influence of microenvironmental conditions in
Last updated on: 23-02-2024 - 16:20
Contact: Cyril Corbet
Organisation: Université Catholique de Louvain (UCL)
Status: Published in peer reviewed journal
Adult intestinal stem cells are grown into closed 3D structures with protruding buds and a luminal compartment. These 3D structures are produced from the stem cells present in the base of crypts isolated from rectal mucosa samples that can be collected by suction or forceps biopsy. The crypts are
Last updated on: 22-02-2024 - 11:15
Contact: Anabela Ramalho
Organisation: Katholieke Universiteit Leuven (KUL)
Status: Published in peer reviewed journal
Drug-induced phospholipidosis (DIPL) is a metabolic disorder characterized by an excessive intracellular accumulation of phospholipids caused by cationic drugs. Hepatic cells derived from human skin are evaluated as an in vitro model to investigate DIPL and its mechanisms. Human skin stem cells
Last updated on: 20-02-2024 - 11:27
Contact: Cannot be disclosed
Organisation: Vrije Universiteit Brussel (VUB)
Status: History of use
Adverse outcome pathway (AOP) networks are versatile tools in toxicology and risk assessment that capture and visualize mechanisms driving toxicity originating from various data sources. They share a common structure consisting of a set of molecular initiating events and key events, connected by key
Last updated on: 20-02-2024 - 09:27
Contact: Cannot be disclosed
Organisation: Vrije Universiteit Brussel (VUB)
Status: Published in peer reviewed journal
The application of liver organoids is very promising in the field of liver tissue engineering; however, it is still facing some limitations. One of the current major limitations is the matrix in which they are cultured. The mainly undefined and murine-originated tumor matrices derived from
Last updated on: 22-01-2024 - 17:28
Contact: Nathan Carpentier
Organisation: Ghent University (UGent)
Status: Published in peer reviewed journal
The culture of primary human synoviocytes provides an excellent cellular model for studying the normal and pathological physiology of synoviocytes and the development of joint diseases. Human primary synoviocytes can either be provided by commercial suppliers or isolated from fresh biological
Last updated on: 17-01-2024 - 11:32
The method is about infection of human epidermis in culture by anthropophilic dermatophytes of Trichophyton rubrum species.
Last updated on: 19-12-2023 - 19:21
Contact: Yves Poumay
Organisation: Université de Namur (UNamur)
Status: Published in peer reviewed journal
Method to culture human epidermal keratinocytes and seed them for tissue reconstruction at the air-liquid interface over a polycarbonate porous membrane.
Last updated on: 19-12-2023 - 19:19
Contact: Yves Poumay
Organisation: Université de Namur (UNamur)
Status: Published in peer reviewed journal
Fiber biopersistence is a key factor in understanding the pathogenicity of man-made vitreous fibres (MMVF). Today, compliance to Note Q in Annex VI of Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures may only be demonstrated via in vivo
Last updated on: 19-12-2023 - 19:17
Contact: Léa Hiéronimus
Organisation: Eurima is the European Insulation Manufacturers Association
Status: Still in development, Internally validated, Published in peer reviewed journal
